Invitrogen™ HTR1F Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532864

Catalog No. PIPA532864

Description

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon (100%); Gorilla, Monkey, Bovine, Elephant, Horse, Rabbit, Guinea pig, Platypus (94%); Dog, Bat (88%); Rat, Panda (81%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

5-HT1F is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. 5-HT1F is a member of the GPCR family. Expression of 5-HT1F has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.

Specifications

• Antigen: HTR1F
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HTR1F
• Gene Alias: 5-HT-1E-beta; 5ht1f; 5-HT1F; 5-HT-1F; 5HT1F Receptor; 5-HT1f receptor; 5HT6; 5-hydroxytryptamine (serotonin) receptor 1E beta; 5-hydroxytryptamine (serotonin) receptor 1F; 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled; 5-hydroxytryptamine receptor 1F; Htr1eb; HTR1EL; HTR1F; MR77; Serotonin receptor 1F; serotonin receptor gene (similar to Mm Htr1eb)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3355
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P30939
• Gene Symbols: HTR1F
• Immunogen: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human 5HT1F Receptor.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG