Invitrogen™ HTR5B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102047

Catalog No. PIPA5102047

Description

Antibody detects endogenous levels of total HTR5B.

SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134), is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus.

Specifications

• Antigen: HTR5B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Htr5b
• Gene Alias: 5ht5b; 5-HT5B; 5-HT-5B; 5-hydroxytryptamine (serotonin) receptor 5B; 5-hydroxytryptamine receptor 5B; Htr5b; MR22; protein-tyrosine-phosphatase (EC 3.1.3.48) Ly-5 precursor (B-cell variant); REC17; Serotonin receptor 5B
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15564, 79247
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P31387, P35365
• Gene Symbols: Htr5b
• Immunogen: A synthesized peptide derived from rat HTR5B(Accession P35365), corresponding to amino acid residues V279-M299.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov