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HTRA2 Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 157751AP

Catalog No. 50-173-0469


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Description

Description

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3). Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli. This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP. Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.
Specifications

Specifications

HTRA2
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O43464, Q9JIY5
HtrA serine peptidase 2, HTRA2, OMI, PARK13, PRSS25, Serine protease 25, Serine proteinase OMI
Rabbit
IgG
150 μL
-20°C
Primary
27429, 297376, 64704
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
HTRA2
Liquid
Htra2
HTRA2 Fusion Protein Ag8455
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate, Rat
Documents
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