Invitrogen™ Human CXCL12 Recombinant Protein

Description

Recombinant Protein

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: P48061
• For Use With (Application): Control, ELISA, Immunohistochemistry, Western Blot
• Formulation: PBS with 0.01% Tween 80, 5% mannitol, 5% trehalose and no preservative; pH 7.4
• Gene ID (Entrez): 6387
• Molecular Weight (g/mol): 8.6 kDa
• Name: Human CXCL12
• Quantity: 50 μg
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; AI174028; C Cmotif chemokine; C x C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; Scyb12; Sdf1; SDF-1; SDF-1 gamma; SDF1A; SDF-1 A; SDF-1-alpha(3-67); SDF1B; SDF-1 b; SDF-1-beta(3-72); Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tlsfa; TLSF-a; Tlsfb; TLSF-b; Tpar1
• Common Name: CXCL12
• Gene Symbol: CXCL12
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: Human CXCL12 isoform beta, amino acids Lys22-Met93 (Accession # P48061-1)
• Content And Storage: -20°Cor to +80°C if preferred
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: >95% by SDS-PAGE

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov