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Gibco™ Human alpha-Defensin 1 Recombinant Protein, PeproTech®

Catalog No. 30042250UG
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Quantity:
1 mg
100 μg
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250 μg
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500 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Human NP-1 is a 3.4 kDa protein containing 30 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P59665
For Use With (Application) ELISA, Functional Assay, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 1667
Molecular Weight (g/mol) 3.4 kDa
Name Human alpha-Defensin 1
Quantity 250 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias alpha-defensin 1; Cryptdin-1; DEF1; Defa1; DEFA1B; DEFA2; Defcr; Defcr1; defensin alpha 1; defensin related cryptdin peptide 1; defensin, alpha 1; defensin, alpha 1, myeloid-related sequence; defensin, alpha 2; defensin-1; defensin-related cryptdin peptide; HNP-1; HNP-2; HP 1-56; HP1; HP-1; HP-2; MRS; myeloid-related sequence; neutrophil defensin 1; Neutrophil defensin 2
Common Name DEFA1
Gene Symbol DEFA1
Biological Activity Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence ACYCRIPACI AGERRYGTCI YQGRLWAFCC
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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