Gibco™ Human ANGPTL-7 Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Human ANGPTL-7 is a glycoprotein that migrates by SDS-PAGE analysis at an apparent molecular weight of 40-50 kDa under reduced conditions, and contains 328 amino acid residues including a C-terminal His-tag. The calculated molecular weight of Recombinant Human ANGPTL-7 is 38.2 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Angptl7 (angiopoietin-like 7), alternately known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein that is expressed specifically in the stromal layer of cornea. Angptl7 forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain. Overexpressed in patients with glaucoma, Angptl7 serves as a potential therapeutic target for glaucoma and has been found to increase collagen expression. The gene encoding Angptl7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Specifications

• Accession Number: O43827
• For Use With (Application): ELISA, Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 10218
• Molecular Weight (g/mol): 38.2 kDa
• Name: Human ANGPTL-7
• Quantity: 1 mg
• Source: Insect cells
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: angiopoietin like 7; angiopoietin-like 7; Angiopoietin-like factor; angiopoietin-like factor (CDT6); angiopoietin-like protein 7; Angiopoietin-related protein 7; ANGPTL7; AngX; CDT6; Cornea-derived transcript 6 protein; dJ647M16.1; UNQ313/PRO356
• Common Name: ANGPTL7
• Gene Symbol: ANGPTL7
• Biological Activity: Measured by its binding ability to recombinant alphavbeta3 integrin in a functional ELISA.
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: QKLSKHKTPA QPQLKAANCC EEVKELKAQV ANLSSLLSEL NKKQERDWVS VVMQVMELES NSKRMESRLT DAESKYSEMN NQIDIMQLQA AQTVTQTSAD AIYDCSSLYQ KNYRISGVYK LPPDDFLGSP ELEVFCDMET SGGGWTIIQR RKSGLVSFYR DWKQYKQGFG SIRGDFWLGN EHIHRLSRQP TRLRVEMEDW EGNLRYAEYS HFVLGNELNS YRLFLGNYTG NVGNDALQYH NNTAFSTKDK DNDNCLDKCA QLRKGGYWYN CCTDSNLNGV YYRLGEHNKH LDGITWYGWH GSTYSLKRVE MKIRPEDFKP HHHHHHHH
• Content And Storage: -20°C
• Expression System: Insect cells
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.