Invitrogen™ Human C1orf86 (aa 108-180) Control Fragment Recombinant Protein

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (58%), Rat (58%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58555 (PA5-58555. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.

Specifications

• Accession Number: Q6NZ36
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 199990
• Name: Human C1orf86 (aa 108-180) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 2610002J02Rik; C1orf86; Faap20; FANCA-associated protein of 20 kDa; Fanconi anemia core complex associated protein 20; Fanconi anemia core complex-associated protein 20; Fanconi anemia-associated protein of 20 kDa; FP7162; likely orthologue of H. sapiens chromosome 1 open reading frame 86 (C1orf86); LOC362678; RGD1308923; RIKEN cDNA 2610002J02 gene
• Common Name: C1orf86
• Gene Symbol: FAAP20
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: GGHLESPARSLPQRPAPDPCRAPRVEQQPSVEGAAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining