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Invitrogen™ Human Cluster of Differentiation 6/CD6 ELISA Kit

Catalog No. p-7219288
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Quantity:
5 x 96 Tests
96 Tests

ELISA

Human Cluster of Differentiation 6/CD6 quantitates human Cluster of Differentiation 6/CD6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cluster of Differentiation 6/CD6.

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number CD6; CD6 antigen; CD6 antigen, Tp120; CD6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
Assay Range 0.23 to 50 ng/mL
Assay Sensitivity 0.23 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 923
Gene Symbol CD6
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target CD6
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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