Invitrogen™ Human Cluster of Differentiation 6/CD6 ELISA Kit

Description

ELISA

Human Cluster of Differentiation 6/CD6 quantitates human Cluster of Differentiation 6/CD6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cluster of Differentiation 6/CD6.

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.

Specifications

• Accession Number: CD6; CD6 antigen; CD6 antigen, Tp120; CD6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
• Assay Range: 0.23 to 50 ng/mL
• Assay Sensitivity: 0.23 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 923
• Gene Symbol: CD6
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: CD6
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins

Safety and Handling

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