Invitrogen™ Human CRIM1 ELISA Kit

Description

ELISA

Human CRIM1 quantitates human CRIM1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CRIM1.

CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.

Specifications

• Accession Number: AU015004; Crim1; CRIM-1; cysteine rich transmembrane BMP regulator 1; cysteine rich transmembrane BMP regulator 1 (chordin like); cysteine rich transmembrane BMP regulator 1 (chordin-like); cysteine-rich motor neuron 1; cysteine-rich motor neuron 1 protein; Cysteine-rich repeat-containing protein S52; Processed cysteine-rich motor neuron 1 protein; S52; UNQ1886/PRO4330
• Assay Range: 0.041 to 10 ng/mL
• Assay Sensitivity: 0.041 ng/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 51232
• Gene Symbol: CRIM1
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: CRIM1
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins