Human CXCR7/RDC-1 Antibody, R&D Systems™

Mouse Monoclonal Antibody

Supplier:  R&D Systems MAB4227R100

Catalog No. MAB4227R-100

Description

CXCR7/RDC-1 Monoclonal specifically detects CXCR7/RDC-1 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, CyTOF-ready.

Specifications

• Antigen: CXCR7/RDC-1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: Lyophilized from a 0.2μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2μm filtered solution in PBS.
• Gene Alias: ACKR3, chemokine (C-X-C motif) receptor 7, Chemokine orphan receptor 1CMKOR1C-X-C chemokine receptor type 7, CMKOR1, CXCR7, CXC-R7, CXCR-7, G protein-coupled receptor, GPR159, GPR159G-protein coupled receptor 159, RDC-1, RDC1G-protein coupled receptor RDC1 homolog
• Immunogen: NS0 mouse myeloma cell line transfected with human CXCR7/RDC-1 Met1-Lys362 (Gly131Ser) Accession # AAA62370
• Quantity: 100 μg
• Gene ID (Entrez): 57007
• Reconstitution: Reconstitute at 0.5mg/mL in sterile PBS.
• Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Isotype: IgG2a

• Applications: CyTOF, Flow Cytometry, Immunohistochemistry
• Clone: 358426R
• Dilution: Flow Cytometry 0.25μg/10⁶ cells, Immunohistochemistry 5-25μg/mL, CyTOF-ready
• Gene Accession No.: AAA62370
• Host Species: Mouse
• Purification Method: Protein A or G purified from hybridoma culture supernatant
• Primary or Secondary: Primary
• Test Specificity: Detects human CXCR7/RDC-1 in direct ELISAs. In flow cytometry, reacts specifically with five distinct human CXCR7 transfectants, but does not react with their respective parental lines or mouse CXCR7 transfectants. In flow cytometry, also reacts with monocytes expressing CXCR7, but does not react with MCF-7 cells which have been reported to have surface-expressing CXCR7 using clone 11G8. Due to the conflicting reports published, use of monoclonal MAB4227 may result in an underestimation of CXCR7 expression on certain cell types.
• Target Species: Human
• Form: Supernatant