Invitrogen™ Human Factor Xa Native Protein

Description

Native Protein

The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. RP-43114 contains native human Factor Xa protein. RP-43114, RP-43117, and RP43118 may be used as controls in many immunological assays. RP-43114 is the active version of Factor Xa. The EGR version (RP-43117) contains the tripeptide chloromethyl ketone inhibitor EGRck, which irreversibly blocks the active-site of Xa. The DEGR version (RP-43118) contains the fluorescent inhibitor Dansyl-EGRck (DEGR), which irreversibly blocks the active-site of Xa. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.

Specifications

• Accession Number: P00742
• Concentration: 7 mg/mL
• For Use With (Application): Control
• Formulation: 50% water with 50% glycerol and no preservative
• Gene ID (Entrez): 2159
• Molecular Weight (g/mol): 46 kDa
• Name: Human Factor Xa
• Quantity: 100 μg
• Source: Human
• Regulatory Status: RUO
• Gene Alias: Activated factor Xa heavy chain; Coagulation factor X; F10; F10a; Factor x heavy chain; Factor x light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
• Common Name: Factor Xa
• Gene Symbol: F10
• Conjugate: Unconjugated
• Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Protein Subtype: Native