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Invitrogen™ Human IgG4 Recombinant Rabbit Monoclonal Antibody (ST05-12)
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Catalog No. PIMA532169
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100 μL
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PIMA532169 100 μL
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Catalog No. PIMA532169 Supplier Invitrogen™ Supplier No. MA532169
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Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Human IgG4, also known as human immunoglobulin G4, is a subclass of human IgG antibodies that is produced by the immune system in response to antigens. It is the least abundant subclass of IgG in the blood and plays a minor role in defense against pathogens. IgG4 works by binding to specific antigens and promoting their clearance from the body through various mechanisms, including phagocytosis and complement activation. IgG4 is also involved in other immune responses, such as immune tolerance and suppression of inflammation. Human IgG4 can be used in research to study the immune response to pathogens and to develop diagnostic tests and therapeutic interventions for infectious and autoimmune diseases.
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Specifications

Antigen Human IgG4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone ST05-12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% Glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene IGHG4
Gene Accession No. P01861
Gene Alias IGHG4; Immunoglobulin G; Immunoglobulin G4; immunoglobulin heavy constant gamma 4 (G4m marker); ImmunoglobulinG
Gene Symbols IGHG4
Host Species Rabbit
Immunogen Synthetic peptide within Human IgG4 aa 85-129.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3503
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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