Human IL-18 R beta/IL-1 R7 Antibody, R&D Systems™

Mouse Monoclonal Antibody

Supplier:  R&D Systems MAB118

Catalog No. MAB118

Description

IL-18 R beta/IL-1 R7/ACPL Monoclonal specifically detects IL-18 R beta/IL-1 R7/ACPL in Human samples. It is validated for Western Blot, Flow Cytometry, CyTOF-ready.

Specifications

• Antigen: IL-18 R beta/IL-1 R7/ACPL
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
• Gene Alias: Accessory protein-like, AcPL, CD218 antigen-like family member B, CD218b, CD218b antigen, CDw218b, IL-1 R7, IL-18 receptor accessory protein, IL-18 receptor beta, IL18R beta, IL-18RAcP, IL18RAP, IL-18Rb, IL18RB, IL-18Rbeta, IL-18R-beta, IL-1R accessory protein-like, IL1R7, IL-1R7, IL-1R-7, IL-1RAcPL, interleukin 18 receptor accessory protein, Interleukin-1 receptor 7, interleukin-18 receptor accessory protein, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, MGC120589, MGC120590
• Host Species: Mouse
• Purification Method: Protein A or G purified from hybridoma culture supernatant
• Regulatory Status: RUO
• Gene ID (Entrez): 8807
• Reconstitution: Reconstitute at 0.5 mg/mL in sterile PBS.
• Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Isotype: IgG2b

• Applications: Western Blot, Flow Cytometry, CyTOF
• Clone: 132029
• Dilution: Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, CyTOF-ready
• Gene Accession No.: O95256
• Gene Symbols: IL18RAP
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human IL-18 R beta/IL-1 R7 Met1-Arg356 Accession # O95256
• Quantity: 500 μg
• Primary or Secondary: Primary
• Test Specificity: Detects human IL-18 R beta/IL-1 R7 in direct ELISAs and Western blots. In direct ELISAs, 15% cross-reactivity with recombinant human (rh) IL-1 RII is observed and 2% cross-reactivity with rhIL-1 R9 is observed. Also in direct ELISAs, no cross-reactivity with rhIL-1 RI, rhIL-1 RacP/IL-1 R3, rhIL-1 R4, rhIL-18 R alpha/IL-1 R5, rhIL-1 R6, rhIL-1 R8, or recombinant mouse (rm) IL-18 R beta/IL-1 R7 is observed. In Western blots, approximately 100% cross-reactivity with rmIL-18 R beta is observed and no cross-reactivity with rhIL-18 R alpha/IL-1 R5, rhIL-1 RacP/IL-1 R3, rhIL-1 RI, rhIL-1 RII, or rhIL-1 Rrp2/IL-1 R6 is observed.
• Target Species: Human
• Form: Purified