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Human IL-2 R beta Antibody, R&D Systems™
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Catalog No. AF224SP
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25 μg
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AF224SP 25 μg
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Catalog No. AF224SP Supplier R&D Systems Supplier No. AF224SP
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Description

Goat Polyclonal Antibody has been used in 2 publications

IL-2 R beta Polyclonal specifically detects IL-2 R beta in Human samples. It is validated for Western Blot, Neutralization.

Specifications

Antigen IL-2 R beta
Applications Western Blot, Neutralization
Classification Polyclonal
Concentration LYOPH
Conjugate Unconjugated
Dilution Western Blot 0.1 ug/mL, Neutralization 10-30 ug/mL
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Accession No. NP_000869
Gene Alias CD122, CD122 antigen, high affinity IL-2 receptor beta subunit, High affinity IL-2 receptor subunit beta, IL-15 R beta, IL-2 receptor subunit beta, IL2R beta, IL-2R subunit beta, IL2RB, IL-2RB, interleukin 15 receptor, beta, interleukin 2 receptor, beta, interleukin-2 receptor subunit beta, P70-75, p75
Gene Symbols IL2RB
Host Species Goat
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-2 R beta Ala27-Asp239 Accession # NP_000869
Purification Method Affinity Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3560
Test Specificity Detects human IL-2 R beta in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) IL-2 R alpha , recombinant mouse (rm) IL-2 R beta , rhIL-2 R gamma , and rhIL-15 R is observed. Is also able to block the cell surface of human IL-2 R beta mediated bioactivities induced by IL-2. For optimal neutralization of IL-2 biological activity on cells expressing the high affinity IL-2 receptors, the use of anti-IL-2 R alpha in conjunction with anti-IL-2 R beta antibodies is recommended.
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Target Species Human
Content And Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype IgG
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