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Invitrogen™ eBioscience™ Human IL-29 (IFN-lambda1) Platinum ELISA Kit Non-distribution product as customer accommodation.

For the quantitative detection of human IL-29.

Manufacturer:  Invitrogen™ BMS2049

 View more versions of this product

Catalog No. 50-179-58


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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human IL-29
Biotin-Conjugate anti-human IL-29 monoclonal antibody
Streptavidin-HRP
Human IL-29 Standard lyophilized, 2ng/mL upon reconstitution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Description

Description

IFN-lambdas constitute a novel family of interferons that mediate the induction of anti-viral protection in a wide variety of cells. There are three members in this family, namely lambda1, lambda2, and lambda3, which are also known as IL-29, IL-28A, and IL-28B, respectively. Similar to type I IFNs, IFN-lambdas activate an intracellular signaling to promote gene expression. IFN-lambdas mediate their anti-viral protection through a class II cytokine receptor complex composed of two essential receptor proteins, CRF2-12/IFN-lambdaR1, which is unique to IFN-lambdas, and CFR2-4/IL-10R2, which is shared with IL-10, IL-22, and IL-26 receptors. The IFN-lambdas, IL-28 and IL-29, have recently been reported to prime dendritic cells to induce proliferation of Foxp3-bearing regulatory T cells. DCs that differentiate in response to IFN-lambdas express high levels of class I and II MHC gene products, but low levels of costimulatory molecules. Moreover, these cells can specifically induce IL-2-dependent proliferation of CD4+CD25+FOXP3+ T cells with contact-dependent suppressive activity.
Specifications

Specifications

Q8IU54
Biotin
282618
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
96 tests
2.0 pg/mL
50μL
Human
1 hr 20 min
Human
IFNL1, Interleukin 29
7.6%
15.6-1,000 pg/mL
ELISA
Colorimetric Microplate Reader
ELISA
RUO
Plasma, Serum, Supernatants
Plasma (50μL), Serum (50μL), Supernatants (50μL)
2-8°C
3 hr 30 min
IFNL1
7.1%
HRP
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