Invitrogen™ Human MR-ProADM ELISA Kit

Catalog No.	Quantity
EEL189	96 Tests

Catalog No. EEL189 Supplier Invitrogen™ Supplier No. EEL189

Description

ELISA

MR-proADM, short for mid-regional proadrenomedullin, is a precursor protein that gives rise to the adrenomedullin (ADM) hormone. It is involved in various physiological processes, particularly in the regulation of cardiovascular function and inflammation. Functionally, MR-proADM is associated with vasodilation, blood pressure regulation, and immune response modulation. It acts as a biomarker for endothelial dysfunction and can be used to assess the severity of certain cardiovascular diseases. Elevated levels of MR-proADM have also been linked to systemic inflammation and sepsis. Structurally, MR-proADM is a protein that consists of a chain of amino acids. It undergoes post-translational processing to generate the active form of ADM, which is a shorter peptide consisting of 52 amino acids. Localization-wise, MR-proADM is primarily produced in various tissues, including the adrenal glands, lungs, and endothelial cells lining blood vessels. It is released into the bloodstream and can be measured as a biomarker to provide insight into cardiovascular health and inflammatory conditions.

Specifications

• Accession Number: P35318
• Assay Range: 15.63 to 1000 pg/mL
• Assay Sensitivity: 9.38 pg/mL
• Conjugate: Unlabeled
• Product Type: ELISA
• Sample Type: Cell Lysates, Plasma, Serum, Tissue Homogenates
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 133
• Gene Symbol: ADM
• Interassay CV: <10
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer
• Label or Dye: Biotin
• Quantity: 96 Tests
• Regulatory Status: RUO
• Sample Volume: Cell Lysate 100 μL, Plasma 100 μL, Serum 100 μL, Tissue Homogenate 100 μL
• Storage Requirements: Refer to product documentation for component specific storage temperature.
• Target: MR-proADM
• Test Time: 1 hrs 20 mins
• Total Assay Time: 2 hrs 30 mins