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Human NRG1-beta 1/HRG1-beta 1 EGF Domain Antibody, R&D Systems™
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Catalog No. MAB3771SP
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MAB3771SP 25 μg
MAB3771100 100 μg
MAB3771500 500 μg
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Description

Mouse Monoclonal Antibody has been used in 2 publications

Neuregulin-1 beta 1/NRG1 beta 1 Monoclonal specifically detects Neuregulin-1 beta 1/NRG1 beta 1 in Human samples. It is validated for ELISA Capture (Matched Antibody Pair).

Specifications

Antigen Neuregulin-1 beta 1/NRG1 beta 1
Applications ELISA
Classification Monoclonal
Clone 147705
Conjugate Unconjugated
Dilution ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Accession No. AAA58639
Gene Alias ARIA, GGF, GGF2, Heregulin-1, HGL, HRG, HRG1, HRG1-alpha, HRG1-beta 1, HRGA, MST131, MSTP131, NDF, neuregulin 1, Neuregulin1, Neuregulin1 beta 1, NRG1, NRG1-IT2, SMDF
Gene Symbols NRG1
Host Species Mouse
Immunogen E. coli-derived recombinant human NRG1-beta 1/HRG1-beta 1 Ser2-Lys246 Accession # AAA58639
Purification Method Protein A or G purified from hybridoma culture supernatant
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3084
Test Specificity Detects human NRG1-beta 1 in ELISAs. Recognizes an epitope found in the EGF-like domain of NRG1-beta 1 (amino acids 179-246). It also detects recombinant human SMDF (Sensory and Motor neuron-Derived Factor), but it does not recognize the EGF-like domain of human NRG1-alpha (amino acids 177-241). The epitope is present within amino acids 213-230 of human NRG1-beta 1. This segment is present in all NRG1 beta isoforms, GGF-2 (glial growth factor), and SMDF, but it is absent from NRG1-alpha , NDF43, and NRG1-gamma .
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Target Species Human
Content And Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Form Purified
Isotype IgG1
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