Gibco™ Human SOD1 Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Human SOD is a 16.8 kDa protein containing 160 amino acid residues including an N-terminal His-tag. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Specifications

• Accession Number: P00441
• For Use With (Application): Functional Assay
• Format: Lyophilized
• Formulation: protein with no preservative
• Gene ID (Entrez): 6647
• Molecular Weight (g/mol): 16.8 kDa
• Name: Human SOD1
• Purification Method: HPLC, SDS-PAGE
• Quantity: 10 μg
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/μg
• Gene Alias: ALS; als1; Amyotrophic lateral sclerosis 1 (ALS1); B430204E11Rik; Cu(2+)-Zn2+ superoxide dismutase; Cu/Zn SOD; Cu/Zn superoxide dismutase; Cu/Zn-SOD; CuZn superoxide dismutase; Cu-Zn superoxide dismutase; Cu-Zn superoxide dismutase C-terminal fragment (150 AA); CuZnSOD; Cu-Zn-superoxide dismutase; epididymis secretory protein Li 44; HEL-S-44; HGNC:11179; homodimer; hSod1; indophenoloxidase A; Indophenoloxidase A (IPOA); Ipo1; Ipo-1; ipoa; similar to superoxide dismutase; sod; SOD, soluble; sod1; Sod-1; sod1.S; sod1-a; sod1-b; SOD1L1; SODC; superoxide dismutase; superoxide dismutase [Cu-Zn]; Superoxide dismutase [Cu-Zn] A; superoxide dismutase [Cu-Zn] A-like; superoxide dismutase 1; Superoxide Dismutase 1 (SOD1); superoxide dismutase 1 S homeolog; superoxide dismutase 1 soluble; superoxide dismutase 1, soluble; superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)); superoxide dismutase 1, soluble S homeolog; superoxide dismutase, cystolic; XELAEV_18014289mg; XSODA; xsodb
• Common Name: SOD1
• Gene Symbol: SOD1
• Biological Activity: Determined by its ability to decrease superoxide concentration when tested using an SOD colorimetric activity kit.
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: MHHHHHHATK AVCVLKGDGP VQGIINFEQK ESNGPVKVWG SIKGLTEGLH GFHVHEFGDN TAGCTSAGPH FNPLSRKHGG PKDEERHVGD LGNVTADKDG VADVSIEDSV ISLSGDHCII GRTLVVHEKA DDLGKGGNEE STKTGNAGSR LACGVIGIAQ
• Content And Storage: -20°C
• Activity: Determined by its ability to decrease superoxide concentration when tested using an SOD colorimetric activity kit.
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥98% by SDS-PAGE gel and HPLC analyses.