Gibco™ Human Wnt-9b Recombinant Protein, PeproTech®

Description

Recombinant Protein

120-49-1MG will be provided as 10 x 100 μg (120-49-100UG). 120-49-250UG will be provided as multiple 50 μg (120-49-50UG) and 100 μg (120-49-100UG) vials. 120-49-500UG will be provided as 5 x 100 μg (120-49-100UG). Recombinant Human Wnt-9b is a monomeric glycoprotein containing 335 amino acid residues and has a calculated molecular weight of 36.9 kDa. Due to glycosylation, Recombinant Human Wnt-9b migrates at an apparent molecular weight of approximately 49-54 kDa by SDS-PAGE analysis under non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

WNT9B, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.

Specifications

• Accession Number: O14905
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 7484
• Molecular Weight (g/mol): 36.9 kDa
• Name: Human Wnt-9 b
• Quantity: 100 μg
• Source: CHO cells
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: clf; clf1; protein Wnt-14 b; Protein Wnt-15; Protein Wnt-9 b; UNQ6973/PRO21956; wingless-type MMTV integration site 15; wingless-type MMTV integration site 9 B; wingless-type MMTV integration site family member 9 B; wingless-type MMTV integration site family, member 15; wingless-type MMTV integration site family, member 9 B; Wnt family member 9 B; Wnt14b; wnt-14 b; Wnt15; wnt-15; Wnt9b
• Common Name: WNT9B
• Gene Symbol: Wnt9b
• Biological Activity: Determined by its ability to induce alkaline phosphatase production by CCL-226 cells.
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: SYFGLTGREV LTPFPGLGTA AAPAQGGAHL KQCDLLKLSR RQKQLCRREP GLAETLRDAA HLGLLECQFQ FRHERWNCSL EGRMGLLKRG FKETAFLYAV SSAALTHTLA RACSAGRMER CTCDDSPGLE SRQAWQWGVC GDNLKYSTKF LSNFLGSKRG NKDLRARADA HNTHVGIKAV KSGLRTTCKC HGVSGSCAVR TCWKQLSPFR ETGQVLKLRY DSAVKVSSAT NEALGRLELW APARQGSLTK GLAPRSGDLV YMEDSPSFCR PSKYSPGTAG RVCSREASCS SLCCGRGYDT QSRLVAFSCH CQVQWCCYVE CQQCVQEELV YTCKH
• Content And Storage: -20°C
• Expression System: CHO cells
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.