Invitrogen™ HUS1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565122

Catalog No. PIPA565122

Description

Immunogen sequence: GASSLKLQLTH KRRPSLTVAV ELVSSLGRAR SVVHDLPVRV LPRRVWRDCL PPSLRASDAS IRLPRWRTLR SIVERMANVG SHVL Highest antigen sequence identity to the following orthologs - mouse 67%, rat 66%.

HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

Specifications

• Antigen: HUS1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hus1b
• Gene Alias: Checkpoint protein HUS1B; hHUS1B; HUS1 checkpoint clamp component B; HUS1 checkpoint homolog b; HUS1 checkpoint homolog b (S. pombe); Hus1 homolog b (S. pombe); Hus1b; MGC126746; MGC126748; mHUS1B; RP11-532F6.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 135458
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NHY5
• Gene Symbols: Hus1b
• Immunogen: Recombinant Human HUS1B. Recombinant protein control fragment (Product #RP-105886).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG