Invitrogen™ HUS1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593237

Catalog No. PIPA593237

Description

Immunogen sequence: MKFRAKITGK GCLELFIHVS GTVARLAKVC VLRVRPDSLC FGPAGSGGLH EARLWCEVRQ GAFQQFRMEG VSEDLDEIHL ELTAEHLSRA ARSAAGASSL KLQLTHKRRP SLTVAVELVS SLGRARSVVH DLPVRVLPRR VWRDCLPPSL RASDASIRLP RWRTLRSIVE RMANVGSHVL VEANLSGRMT LSIETEVVSI QSYFKNLGNP PQSAVGVPEN RDLESMVQVR VDNRKLLQFL EGQQIHPTTA LCNIWDNTLL QLVLVQEDVS LQYFIPAL; Positive Samples: LO2, Jurkat, Mouse spleen, Mouse thymus, Rat testis, Rat thymus.

HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

Specifications

• Antigen: HUS1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hus1b
• Gene Alias: Checkpoint protein HUS1B; hHUS1B; HUS1 checkpoint clamp component B; HUS1 checkpoint homolog b; HUS1 checkpoint homolog b (S. pombe); Hus1 homolog b (S. pombe); Hus1b; MGC126746; MGC126748; mHUS1B; RP11-532F6.1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 135458, 210554, 691382
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.21 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8K572, Q8NHY5
• Gene Symbols: Hus1b
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human HUS1B (NP_6837622).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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