Invitrogen™ HUS1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103493

Catalog No. PIPA5103493

Description

Antibody detects endogenous levels of total HUS1B.

HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.

Specifications

• Antigen: HUS1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hus1b
• Gene Alias: Checkpoint protein HUS1B; hHUS1B; HUS1 checkpoint clamp component B; HUS1 checkpoint homolog b; HUS1 checkpoint homolog b (S. pombe); Hus1 homolog b (S. pombe); Hus1b; MGC126746; MGC126748; mHUS1B; RP11-532F6.1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 135458, 691382
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8NHY5
• Gene Symbols: Hus1b
• Immunogen: A synthesized peptide derived from human HUS1B(Accession Q8NHY5), corresponding to amino acid residues F66-V116.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov