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HVCN1 Rabbit anti-Human, Polyclonal, Proteintech
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Catalog No. 501729255 Shop All Proteintech Group Inc Products
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50-172-9255 150 μL
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Catalog No. 50-172-9255 Supplier Proteintech Group Inc Supplier No. 141621AP150UL
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Rabbit Polyclonal Antibody

HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell maligcies on continued signaling via the B cell antigen receptor.

Specifications

Antigen HVCN1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene HVCN1
Gene Accession No. Q96D96
Gene Alias HV1, HVCN1, VSOP
Gene Symbols HVCN1
Host Species Rabbit
Immunogen HVCN1 Fusion Protein Ag5350
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84329
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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