Invitrogen™ HYAL1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142277

Catalog No. PIPA5142277

Description

Additional Information: This antibody is expected to recognise isoform 1 (NP_009296.1), isoform 3 (NP_695015.1) and isoform 5 (NP_695017.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: HYAL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HYAL1
• Gene Alias: Hya1; HYAL1; Hyal-1; Hyaluronidase; hyaluronidase 1; hyaluronidase-1; hyaluronoglucosaminidase 1; hyaluronoglucosaminidase-1; LUCA1; LuCa-1; Lung carcinoma protein 1; MPS9; NAT6; plasma hyaluronidase; tumor suppressor LUCA-1
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 3373
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q12794
• Gene Symbols: HYAL1
• Immunogen: Peptide with sequence ENTRTKESCQAIKEY.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG