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Invitrogen™ HYAL2 Polyclonal Antibody
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Catalog No. PIPA595061
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100 μg
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PIPA595061 100 μg
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Catalog No. PIPA595061 Supplier Invitrogen™ Supplier No. PA595061
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: HELA whole cell, SMMC whole cell, COLO320 whole cell, MCF-7 whole cell, HT1080 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HYAL2
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene HYAL2
Gene Accession No. O35632, Q12891, Q9Z2Q3
Gene Alias AI256841; AU020858; AW555733; HYAL2; Hyal-2; Hyaluronidase; hyaluronidase 2; hyaluronidase-2; hyaluronoglucosaminidase 2; hyaluronoglucosaminidase-2; LUCA2; LuCa-2; lung carcinoma protein 2; lysosomal hyaluronidase; PH20 homolog; PH-20 homolog
Gene Symbols HYAL2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human HYAL2 (142-157aa VRNWQDKDVYRRLSRQ).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15587, 64468, 8692
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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