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Invitrogen™ HYAL2 Polyclonal Antibody
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Catalog No. PIPA5115387
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PIPA5115387 100 μL
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Catalog No. PIPA5115387 Supplier Invitrogen™ Supplier No. PA5115387
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total HYAL2.

This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HYAL2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene HYAL2
Gene Accession No. O35632, Q12891, Q9Z2Q3
Gene Alias AI256841; AU020858; AW555733; HYAL2; Hyal-2; Hyaluronidase; hyaluronidase 2; hyaluronidase-2; hyaluronoglucosaminidase 2; hyaluronoglucosaminidase-2; LUCA2; LuCa-2; lung carcinoma protein 2; lysosomal hyaluronidase; PH20 homolog; PH-20 homolog
Gene Symbols HYAL2
Host Species Rabbit
Immunogen A synthesized peptide derived from human HYAL2(Accession Q12891), corresponding to amino acid residues G204-L254.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15587, 64468, 8692
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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