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Invitrogen™ HYD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536085

Catalog No. PIPA536085


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Description

Description

This antibody detects endogenous protein at a molecular weight of 309 kDa. Purity is >95% by SDS-PAGE.

EDD (for E3 identified by Differential Display) is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

HYD
Polyclonal
Unconjugated
UBR5
CH D1S3362; DD5; E3 identified by differential display; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase, HECT domain-containing 1; ECGF1; Edd; Edd1; EDG1; EDG-1; extraembryonic development; HECT-type E3 ubiquitin transferase UBR5; hHYD; HYD; Hyperplastic discs protein homolog; KIAA0896; Progestin-induced protein; Rat100; S1P receptor 1; S1P receptor Edg-1; S1P1; S1PR1; ubiquitin protein ligase E3 component n-recognin 5; Ubr5
Rabbit
Antigen affinity chromatography
RUO
117060, 51366, 70790
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
O95071, Q62671, Q80TP3
UBR5
Synthetic peptide corresponding to amino acids 1-50 of human HYD.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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