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Invitrogen™ HYD Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA536085
Description
This antibody detects endogenous protein at a molecular weight of 309 kDa. Purity is >95% by SDS-PAGE.
EDD (for E3 identified by Differential Display) is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.
Specifications
HYD | |
Polyclonal | |
Unconjugated | |
UBR5 | |
CH D1S3362; DD5; E3 identified by differential display; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase, HECT domain-containing 1; ECGF1; Edd; Edd1; EDG1; EDG-1; extraembryonic development; HECT-type E3 ubiquitin transferase UBR5; hHYD; HYD; Hyperplastic discs protein homolog; KIAA0896; Progestin-induced protein; Rat100; S1P receptor 1; S1P receptor Edg-1; S1P1; S1PR1; ubiquitin protein ligase E3 component n-recognin 5; Ubr5 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
117060, 51366, 70790 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
O95071, Q62671, Q80TP3 | |
UBR5 | |
Synthetic peptide corresponding to amino acids 1-50 of human HYD. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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