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Hydroxylamine, 50% aq. soln.
Description
Hydroxylamine is a reactant used for the preparation of hydroxyaminoguanidines which are anti-cancer agents, carboxamide derivatives of ofloxacin and human immunodeficiency virus (HIV) integrase inhibitors. It reacts with chlorosulfonic acid to give hydroxylamine-O-sulfonic acid, a useful reagent in the synthesis of caprolactam. It is commonly used as a reducing agent in myriad of organic and inorganic reactions. It acts as an antioxidant for fatty acids. It is widely used to prepare oximes, an important functional group.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Hydroxylamine is a reactant used for the preparation of hydroxyaminoguanidines which are anti-cancer agents, carboxamide derivatives of ofloxacin and human immunodeficiency virus (HIV) integrase inhibitors. It reacts with chlorosulfonic acid to give hydroxylamine-O-sulfonic acid, a useful reagent in the synthesis of caprolactam. It is commonly used as a reducing agent in myriad of organic and inorganic reactions. It acts as an antioxidant for fatty acids. It is widely used to prepare oximes, an important functional group.
Solubility
Miscible with water, liquid ammonia and methanol. Slightly miscible with ether, benzene, carbon disulfide and chloroform.
Notes
It can violently decompose at elevated temperatures. May be shock-sensitive if dry. Do not heat over 500C. Incompatible with bases, oxidizing agents, nitrates, nitrites, heavy metals, rubber, metals, epoxides and polyester.

Specifications
Specifications
Boiling Point | 107°C to 114°C |
Melting Point | 7°C |
Quantity | 100 mL |
Assay Percent Range | 0.5 |
Linear Formula | NH2OH |
UN Number | UN3266 |
Beilstein | 1098214 |
Flash Point | None |
Merck Index | 14,4828 |
Solubility Information | Miscible with water,liquid ammonia and methanol. Slightly miscible with ether,benzene,carbon disulfide and chloroform. |
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Safety and Handling
Hazard Category | H290-H302+H312-H315-H317-H318-H335-H351-H373 |
Hazard Statement | GHS H Statement H318-H351-H373-H302-H317-H335-H315 |
Precautionary Statement | P201-P202-P234-P260-P264b-P270-P271-P272-P280g-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P310-P312-P330-P333+P313-P362-P372-P373-P380-P390-P501c |
DOTInformation | Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUID, BASIC, INORGANIC, N.O.S. |
EINECSNumber | 232-259-2 |
RTECSNumber | NC2975000 |
TSCA | Yes |
Recommended Storage | Ambient temperatures |
RUO – Research Use Only
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