Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 72925

Tocris Bioscience™ I 432
GREENER_CHOICE

Catalog No. 72925
Change view
Click to view available options
Quantity:
5 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
72-925 5 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. 72-925 Supplier Tocris Bioscience™ Supplier No. 7292/5
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

TMPRSS2 Inhibitor

I 432 is a TMPRSS2 (transmembrane serine proteinase 2) inhibitor (Ki =0.9 nM). It blocks influenza virus propagation in airway epithelial cells. In IPEC-J2 pig jejunal epithelial cells, I 432 (50 μM) inhibits TMPRSS2 without affecting cell viability after 48 h treatment.

Specifications

Chemical Name or Material 3-[(2 S)-3-[4-(2-Aminoethyl)-1-piperidinyl]-2-[[(2 ',4 '-dichloro[1,1 '-biphenyl]-3-yl)sulfonyl]amino]-3-oxopropyl]benzenecarboximidamide ditrifluoroacetate
CAS 1268874-09-4
Quantity 5 mg
Target TMPRSS2
Molecular Formula C29H33Cl2N5O3S0.2 CF3CO2H
Purity 0.98
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.