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Tocris Bioscience™ (R)-PFI 2 hydrochloride
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Catalog No. 489210
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10mg
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Catalog No.
48-921-0 10mg
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Catalog No. 48-921-0 Supplier Tocris Bioscience™ Supplier No. 4892/10
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Description

Potent and selective SETD7 inhibitor

Potent and selective SETD7 histone lysine methyltransferase inhibitor (IC50 = 2 nM). Exhibits >1000-fold selectivity over DNMT1 and a panel of 18 other methyltransferases. Inhibits YAP nuclear translocation and function following activation of the Hippo signaling pathway in MCF7 cells.

Negative Control also available.

Chemical Identifiers

Molecular Formula C23H25F4N3O3S·HCl

Specifications

Quantity 10 mg
Formula Weight 535.98
Chemical Name or Material 8-Fluoro-1,2,3,4-tetrahydro-N-[(1R)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride

Safety and Handling

Recommended Storage Store at +4°C
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