Invitrogen™ IA-6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560857

Catalog No. PIPA560857

Description

Immunogen sequence: KHLSTHEAGS ARALAPGFGS ERGAPLAFAC PLCGAHFPTA DIREKHRLWH AVREELLLPA LAGAPPETSG PSGPSDGSAQ QIFSCKHCPS TF Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.

IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription.

Specifications

• Antigen: IA-6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INSM2
• Gene Alias: IA6; IA-6; INSM transcriptional repressor 2; Insm2; INSM2 variant 1; insulinoma-associated 2; insulinoma-associated protein 2; insulinoma-associated protein IA-6; methylated in liver tumor 1; mlt 1; mlt1; Nbla106; Zinc finger protein IA-6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84684
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96T92
• Gene Symbols: INSM2
• Immunogen: Recombinant protein corresponding to Human IA-6. Recombinant protein control fragment (Product #RP-100071).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG