Invitrogen™ MHC Class II (I-A/I-E) Monoclonal Antibody (CIa)

Catalog No.	Quantity
PIMA528810	1 mL

Catalog No. PIMA528810 Supplier Invitrogen™ Supplier No. MA528810

Description

Mouse Monoclonal Antibody

MHC Class II (I-A/I-E) Monoclonal Antibody for Flow

MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

• Antigen: MHC Class II (I-A/I-E)
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: CIa
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: BBS with no preservative; pH 8.2
• Gene Alias: Abeta; AI323765; AI845868; cell surface glycoprotein; E-alpha-f; H-2 class II histocompatibility antigen, A beta chain; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ab; H2-Ab; H2-Ab1; H-2Ea; H2-Ea; H2-Ea-ps; H2Eb; H-2Eb; H2-Eb1; H2-iabeta; H2-IE-alpha; histocompatibility 2, class II antigen A, beta 1; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility 2, class II antigen E beta; Ia2; Ia-2; Ia3; Ia-3; Ia4; Ia-4; IAb; I-Ab; I-Abeta; I-Ad; I-Aq; I-E alpha MHC class II; I-E beta MHC class II; I-Ealpha; I-Ed; I-Ek; major histocompatibility complex class II beta chain; major histocompatibility complex H-2E beta chain; MHC class 2; MHC class II antigen A beta; MHC class II antigen E alpha; MHC class II H2-IA-beta-psi; MHC class II IE-b; MHC class II protein; MHC H2-IE-beta cell surface glycoprotein; response to metastatic cancers 1; Rmcs1
• Host Species: Mouse
• Immunogen: Splenic leukocytes from an outbred nine-week-old chicken.
• Purification Method: Purified
• Quantity: 1 mL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Avian, Chicken
• Content And Storage: 4°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgM κ