IAPP Mouse anti-Human, Clone: R10/99, Abnova™

Mouse monoclonal antibody raised against human IAPP.

Supplier:  Abnova Corporation MAB12508

Catalog No. 89-934-333

Description

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq]

Sequence: ATQRLANFLV

Specifications

• Antigen: IAPP
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunofluorescence Immunohistochemistry (Frozen sections) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
• Gene Alias: AMYLIN/DAP/IAP
• Host Species: Mouse
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed)
• Clone: R10/99
• Description: Mouse monoclonal antibody raised against human IAPP.
• Formulation: In tissue culture supernatant (0.09% sodium azide).
• Gene Symbols: IAPP
• Immunogen: A synthetic peptide corresponding to human IAPP.
• Regulatory Status: RUO
• Gene ID (Entrez): 3375
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1