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IAPP Mouse anti-Human, Clone: R10/99, Abnova™

Catalog No. 89934333 Shop All Abnova Corporation Products
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89-934-333 50 μL
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Catalog No. 89-934-333 Supplier Abnova Corporation Supplier No. MAB12508
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Description

Mouse monoclonal antibody raised against human IAPP.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq]

Sequence: ATQRLANFLV

Specifications

Antigen IAPP
Applications Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone R10/99
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against human IAPP.
Dilution Immunofluorescence Immunohistochemistry (Frozen sections) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In tissue culture supernatant (0.09% sodium azide).
Gene Alias AMYLIN/DAP/IAP
Gene Symbols IAPP
Host Species Mouse
Immunogen A synthetic peptide corresponding to human IAPP.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3375
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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