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Invitrogen™ IARS Polyclonal Antibody
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Catalog No. PIPA544246
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100 μL
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PIPA544246 100 μL
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Catalog No. PIPA544246 Supplier Invitrogen™ Supplier No. PA544246
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Description

Rabbit Polyclonal Antibody

Peptide sequence: SKHKPKFTFY DGPPFATGLP HYGHILAGTI KDIVTRYAHQ SGFHVDRRFG Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 86%; Yeast: 100%; Zebrafish: 79%.

IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IARS
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene IARS1
Gene Accession No. P41252
Gene Alias 2510016L12Rik; AI327140; AU044614; E430001P04Rik; fi46h05; FLJ20736; IARS; IARS1; Iarsl; ILERS; ILRS; IRS; isoleucine tRNA ligase 1, cytoplasmic; isoleucine tRNA synthetase; isoleucine--tRNA ligase, cytoplasmic; isoleucine-tRNA synthetase; isoleucyl tRNA synthetase; isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase 1; isoleucyl-tRNA synthetase, cytoplasmic; PRO0785; wu:fi46h05; zgc:63790
Gene Symbols IARS1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human IARS (aa 35-84).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3376
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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