Invitrogen™ IARS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544246

Catalog No. PIPA544246

Description

Peptide sequence: SKHKPKFTFY DGPPFATGLP HYGHILAGTI KDIVTRYAHQ SGFHVDRRFG Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 86%; Yeast: 100%; Zebrafish: 79%.

IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.

Specifications

• Antigen: IARS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IARS1
• Gene Alias: 2510016L12Rik; AI327140; AU044614; E430001P04Rik; fi46h05; FLJ20736; IARS; IARS1; Iarsl; ILERS; ILRS; IRS; isoleucine tRNA ligase 1, cytoplasmic; isoleucine tRNA synthetase; isoleucine--tRNA ligase, cytoplasmic; isoleucine-tRNA synthetase; isoleucyl tRNA synthetase; isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase 1; isoleucyl-tRNA synthetase, cytoplasmic; PRO0785; wu:fi46h05; zgc:63790
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3376
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P41252
• Gene Symbols: IARS1
• Immunogen: Synthetic peptide directed towards the N-terminal of human IARS (aa 35-84).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG