Invitrogen™ IARS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578012

Catalog No. PIPA578012

Description

Positive Control: 293T, A431, HeLa, HepG2 Predicted Reactivity: Mouse (92%), Xenopus laevis (80%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.

Specifications

• Antigen: IARS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IARS1
• Gene Alias: 2510016L12Rik; AI327140; AU044614; E430001P04Rik; fi46h05; FLJ20736; IARS; IARS1; Iarsl; ILERS; ILRS; IRS; isoleucine tRNA ligase 1, cytoplasmic; isoleucine tRNA synthetase; isoleucine--tRNA ligase, cytoplasmic; isoleucine-tRNA synthetase; isoleucyl tRNA synthetase; isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase 1; isoleucyl-tRNA synthetase, cytoplasmic; PRO0785; wu:fi46h05; zgc:63790
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 306804, 3376
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.45 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P41252
• Gene Symbols: IARS1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human IARS. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov