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Invitrogen™ IBTK Polyclonal Antibody
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Catalog No. PIPA554895
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100 μL
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PIPA554895 100 μL
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Catalog No. PIPA554895 Supplier Invitrogen™ Supplier No. PA554895
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LKEICEVALT EKLTLKNAAM LLEFAAMYSA KQLKLSCLQF IGLNMAALLE ARSLDVLSDG VLKDLSEFYR KMIPAMDRRV ITPYQDGPDI SYLEVEDGDI FLKEEINMEQ NHSETMFKKA K Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 79%.

The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IBTK
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IBTK
Gene Accession No. Q9P2D0
Gene Alias Bruton agammaglobulinemia tyrosine kinase inhibitor; BTBD26; BTK-binding protein; BTKI; IBTK; Inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; KIAA1417; RP1-93K22.1
Gene Symbols IBTK
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human IBTK. Recombinant protein control fragment (Product #RP-102180).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25998
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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