Invitrogen™ ICAM-2 Monoclonal Antibody (mIC2/4 (3C4))

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA516837

Catalog No. PIMA516837

Description

This product is a low-endotoxin, preservative-free formulation. Endotoxin level is <0.01 EU/ug. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL.

ICAM-2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. ICAM-2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. Diseases associated with ICAM2 include Colon Carcinoma In Situ.

Specifications

• Antigen: ICAM-2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P35330
• Gene Symbols: ICAM2
• Immunogen: COS cells transfected with murine ICAM-2.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Functional Assay, Immunoprecipitation
• Clone: mIC2/4 (3C4)
• Conjugate: Unconjugated
• Gene: ICAM2
• Gene Alias: CD102; Icam2; ICAM-2; Intercellular adhesion molecule 2; Ly-60; Lymphocyte function-associated AG-1 counter-receptor; RP23-418O11.10-001
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 15896
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid