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Invitrogen™ ICAM-3 Polyclonal Antibody
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Catalog No. PIPA529817
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100 μL
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Catalog No. Quantity
PIPA529817 100 μL
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Catalog No. PIPA529817 Supplier Invitrogen™ Supplier No. PA529817
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Rhesus Monkey (91%), Chimpanzee (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ICAM-3
Applications Western Blot
Classification Polyclonal
Concentration 1.01 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene ICAM3
Gene Accession No. P32942
Gene Alias CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3
Gene Symbols ICAM3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ICAM3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3385
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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