ICAM-3 Polyclonal Antibody, Bethyl Laboratories

Catalog No.	Quantity
50-156-7458	20 μL

Catalog No. 50-156-7458 Supplier Bethyl Laboratories, Inc Supplier No. A304334AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predict

CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.

Specifications

• Antigen: ICAM-3
• Applications: Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene: ICAM3
• Gene Accession No.: P32942
• Gene Alias: CD50, CDW50, ICAM-R, ICAM-3, intercellular adhesion molecule-3
• Gene Symbols: ICAM3
• Host Species: Rabbit
• Immunogen: Between 497 and 547
• Purification Method: Antigen affinity chromatography
• Quantity: 20 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3385
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG