Invitrogen™ ICAM-4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596676

Catalog No. PIPA596676

Description

Immunogen sequence: VGSALGRRTK RAQSPKGSPL APSGTSVPFW VRMSPEFVAV QPGKSVQLNC SNSCPQPQNS SLRTPLRQGK TLRGPGWVSY QLLDVRAWSS LAHCLVTCAG KTRWATSRIT AYSVPGGLLG G; Positive Samples: HepG2, Jurkat, SW480, Mouse brain, Mouse spleen, Mouse heart, Mouse pancreas, Rat brain; Cellular Location: Cell membrane, Single-pass type I membrane protein.

This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: ICAM-4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ICAM4
• Gene Alias: 1810015M19Rik; CD242; CD242 antigen; ICAM4; ICAM-4; Intercellular adhesion molecule 4; intercellular adhesion molecule 4 (Landsteiner-Wiener blood group); intercellular adhesion molecule 4 (LW blood group); intercellular adhesion molecule 4 isoform 3 anitgen LWa; intercellular adhesion molecule 4, Landsteiner-Wiener blood group; Landsteiner-Wiener blood group antigen a; Landsteiner-Wiener blood group glycoprotein; LW; LW blood group protein; LW glycoprotein
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 298702, 3386, 78369
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.43 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q14773, Q9ERM2
• Gene Symbols: ICAM4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human ICAM4 (NP_0010342211).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov