Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ ICI 182,780

Tocris Bioscience™ ICI 182,780
GREENER_CHOICE

Catalog No. 10471
Click to view available options
Quantity:
1 mg
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Estrogen receptor antagonist

ICI 182,780 is a high affinity estrogen receptor antagonist (IC50 = 0.29 nM), devoid of any partial agonism both in vitro and in vivo. ICI 182,780 is a high affinity agonist at the membrane estrogen receptor GPER. ICI 182,780 inhibits MCF-7 human breast cancer cell growth in vitro and shows antitumor activity in mice models. ICI 182,780 penetrates the blood-brain-barrier and has neuronal functional effects in vivo.

Chemical Identifiers

CAS 129453-61-8
Molecular Formula C32H47F5O3S

Specifications

Quantity 1 mg
Formula Weight 606.77
Purity >99%
Molecular Weight (g/mol) 606.777
Chemical Name or Material ICI 182, 780

Safety and Handling

Recommended Storage Store at Room Temperature
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.