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ICI 182,780, Tocris Bioscience™
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Quantity:
1 mg
10 mg
50 mg
Description
ICI 182,780 is a high affinity estrogen receptor antagonist (IC50 = 0.29 nM), devoid of any partial agonism both in vitro and in vivo. ICI 182,780 is a high affinity agonist at the membrane estrogen receptor GPER. ICI 182,780 inhibits MCF-7 human breast cancer cell growth in vitro and shows antitumor activity in mice models. ICI 182,780 penetrates the blood-brain-barrier and has neuronal functional effects in vivo.
Specifications
Quantity | 10 mg |
Formula Weight | 606.77 |
Percent Purity | >99% |
Chemical Name or Material | ICI 182, 780 |
Safety and Handling
Recommended Storage : Store at Room Temperature
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