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Tocris Bioscience™ Idasanutlin

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Quantity:
10 mg
50 mg
Description
Idasanutlin is a potent MDM2 inhibitor (IC50 = 6 nM in binding assay, and 30 nM in cancer cell proliferation assay). Induces p53 stabilisation, cell cycle arrest and apoptosis in cancer cells expressing wildtype p53. Displays inhibition of tumor growth in the SJSA1 tumor xenograft model. Also inhibits MDR-1 at high concentrations.
Specifications
Specifications
Quantity | 50 mg |
Molecular Formula | C31H29Cl2F2N3O4 |
Formula Weight | 616.49 |
Product Type | Inhibitor |
Purity | 98% |
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