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Invitrogen™ IDH1 Polyclonal Antibody
Rabbit Polyclonal Antibody
$209.50 - $511.50
Specifications
Antigen | IDH1 |
---|---|
Concentration | 0.67 mg/mL |
Content And Storage | -20°C |
Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
Classification | Polyclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
PIPA5119232
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Invitrogen™
PA5119232 |
200 μL |
Each for $511.50
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PIPA5121888
|
Invitrogen™
PA5121888 |
20 μL |
Each for $209.50
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Description
IDH1 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.Specifications
IDH1 | |
-20°C | |
Polyclonal | |
Liquid | |
IgG | |
Human | |
IDH1 | |
AI314845; AI788952; cb876; corneal epithelial crystallin; cytosolic NADP+-dependent isocitrate dehydrogenase; cytosolic NADP-isocitrate dehydrogenase; cytosolic NADP-isocitrate dehydrongenase; E030024J03Rik; epididymis luminal protein 216; epididymis secretory protein Li 26; fm90e09; HEL-216; HEL-S-26; ICDH; Id-1; IDCD; IDH; Idh1; Idh-1; IDP; Idpc; im:7143416; isocitrate dehydrogenase (NAD(+)) IDH1; isocitrate dehydrogenase (NADP(+)) 1; isocitrate dehydrogenase (NADP(+)) 1, cytosolic; Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitrate dehydrogenase [NADP] cytoplasmic; isocitrate dehydrogenase 1 (NADP+); isocitrate dehydrogenase 1 (NADP+), soluble; Isocitrate dehydrogenase 1, soluble; Isocitric dehydrogenase; N2690; NAD(+)-specific ICDH; NADP(+)-specific ICDH; NADP+-specific ICDH; NADP-cICDH; NADP-dependent isocitrate dehydrogenase, cytosolic; NADP-dependent isocitrate dehydrogenase, peroxisomal; OTTHUMP00000206464; OTTHUMP00000206465; OTTHUMP00000206466; oxalosuccinate decarboxylase; PICD; wu:fm90e09; YNL037C | |
IDH1 | |
Primary | |
Antigen Affinity Chromatography |
0.67 mg/mL | |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
Unconjugated | |
Rabbit | |
RUO | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
O75874 | |
3417 | |
Recombinant protein Isocitrate Dehydrogenase 1, Soluble. The antigen corresponds to amino acid range 74-333 of the target protein. | |
Antibody |
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