Invitrogen™ IDH3A Monoclonal Antibody (OTI2F11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525007

Catalog No. PIMA525007

Description

IDH3A Monoclonal Antibody for Western Blot, ICC/IF, Flow

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein described here is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Specifications

• Antigen: IDH3A
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P50213, P54836
• Gene Symbols: IDH3A
• Immunogen: Full length human recombinant protein of IDH3A produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Canine
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: OTI2F11
• Conjugate: Unconjugated
• Gene: IDH3A
• Gene Alias: 1110003P10Rik; 1500012E04Rik; AA407078; AI316514; H-IDH alpha; Idh3a; isocitrate dehydrogenase (NAD(+)) 3 alpha; isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha; isocitrate dehydrogenase (NAD+) alpha chain; isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; isocitrate dehydrogenase 3 (NAD(+)) alpha; isocitrate dehydrogenase 3 (NAD+) alpha; isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; NAD(H)-specific isocitrate dehydrogenase alpha subunit; NAD+-specific ICDH
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3419, 479066
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid