IDH3A Mouse anti-Human, Clone: OTI2E9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF500912

Catalog No. 50-165-9954

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predomitly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Specifications

• Antigen: IDH3A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: IDH3A
• Gene Alias: isocitrate dehydrogenase 3 (NAD+) alpha
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3419
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: OTI2E9
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P50213
• Gene Symbols: IDH3A
• Immunogen: Full length human recombit protein of human IDH3A produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1