Invitrogen™ IDH3G Monoclonal Antibody (2A2-1D3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA519176

Catalog No. PIMA519176

Description

Peptide Sequence: MALKVATVAG SAAKAVLGPA LLCRPWEVLG AHEVPSRNIF SEQTIPPSAK YGGRHTVTMI PGDGIGPELM LHVKSVFRHA CVPVDFEEVH VSSNADEEDI RNAIMAIRRN RVALKGNIET NHNLPPSHKS RNNILRTSLD LYANVIHCKS LPGVVTRHKD IDILIVRENT EGEYSSLEHE SVAGVVESLK IITKAKSLRI AEYAFKLAQE SGRKKVTAVH KANIMKLGDG LFLQCCREVA ARYPQITFEN MIVDNTTMQL VSRPQQFDVM VMPNLYGNIV NNVCAGLVGG PGLVAGANYG HVYAVFETAT RNTGKSIANK NIANPTATLL ASCMMLDHLK LHSYAASIRK AVLASMDNEN MHTPDIGGQG TTSEAIQDVI RHIRVINGRA VEA.

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

Specifications

• Antigen: IDH3G
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P51553
• Gene Symbols: Idh3g
• Immunogen: IDH3G (AAH00933, 1 a.a. ~ 393 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 λ

• Applications: ELISA
• Clone: 2A2-1D3
• Conjugate: Unconjugated
• Gene: Idh3g
• Gene Alias: H-IDHG; IDH; IDH3G; IDH-gamma; iso; Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial; isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; isocitrate dehydrogenase 3 (NAD(+)) gamma; isocitrate dehydrogenase 3 (NAD), gamma; isocitrate dehydrogenase 3 (NAD+) gamma; isocitrate dehydrogenase 3 (NAD+), gamma; isocitrate dehydrogenase 3 gamma; isocitrate dehydrogenase 3, gamma; isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, gamma subunit; isocitric dehydrogenase subunit gamma; NAD (H)-specific isocitrate dehydrogenase gamma subunit; NAD(+)-specific ICDH subunit gamma; NAD+-isocitrate dehydrogenase gamma subunit; NAD+-specific ICDH
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3421
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid