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IDH3G Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983862
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50-198-3862 100 μL
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Catalog No. 50-198-3862 Supplier Bioss Supplier No. BS15539R
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Rabbit Polyclonal Antibody

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

Specifications

Antigen IDH3G
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Idh3g
Gene Accession No. P51553
Gene Alias H-IDHG; IDH; Idh3g; IDH-gamma; iso; Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial; Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; isocitrate dehydrogenase 3 (NAD(+)) gamma; isocitrate dehydrogenase 3 (NAD), gamma; isocitrate dehydrogenase 3 (NAD+) gamma; isocitrate dehydrogenase 3 (NAD+), gamma; isocitrate dehydrogenase 3 gamma; isocitrate dehydrogenase 3, gamma; isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, gamma subunit; Isocitric dehydrogenase subunit gamma; NAD (H)-specific isocitrate dehydrogenase gamma subunit; NAD(+)-specific ICDH subunit gamma; NAD+-isocitrate dehydrogenase gamma subunit; NAD+-specific ICDH
Gene Symbols Idh3g
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human IDH3G.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3421
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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