Invitrogen™ Iduronate 2 Sulfatase Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA546990

Catalog No. PIPA546990

Description

In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse IDS is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

Specifications

• Antigen: Iduronate 2 Sulfatase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ids
• Gene Alias: alpha-L-iduronate sulfate sulfatase; AW214631; Ids; Iduronate 2-sulfatase; iduronate 2-sulfatase (Hunter syndrome); iduronate 2-sulfatase 14 kDa chain; Iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; idursulfase; MPS2; SIDS
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3423
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P22304
• Gene Symbols: Ids
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human IDS Ser26-Pro550.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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