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Invitrogen™ Iduronate 2 Sulfatase Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA579439
Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: HELA Cell, SMMC Cell, A549 Cell, MCF-7 Cell, COLO Cell. IHC: Human Placenta Tissue.
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
Specifications
Iduronate 2 Sulfatase | |
Polyclonal | |
Unconjugated | |
Ids | |
alpha-L-iduronate sulfate sulfatase; AW214631; Ids; Iduronate 2-sulfatase; iduronate 2-sulfatase (Hunter syndrome); iduronate 2-sulfatase 14 kDa chain; Iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; idursulfase; MPS2; SIDS | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
3423 | |
-20°C | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
500 μg/mL | |
PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal | |
P22304 | |
Ids | |
A synthetic peptide corresponding to a sequence at the C-terminus of human Iduronate 2 sulfatase (430-448aa ELCREGKNLLKHFRFRDLE). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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