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Invitrogen™ Iduronate 2 Sulfatase Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579439

Catalog No. PIPA579439


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Description

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: HELA Cell, SMMC Cell, A549 Cell, MCF-7 Cell, COLO Cell. IHC: Human Placenta Tissue.

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Iduronate 2 Sulfatase
Polyclonal
Unconjugated
Ids
alpha-L-iduronate sulfate sulfatase; AW214631; Ids; Iduronate 2-sulfatase; iduronate 2-sulfatase (Hunter syndrome); iduronate 2-sulfatase 14 kDa chain; Iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; idursulfase; MPS2; SIDS
Rabbit
Antigen Affinity Chromatography
RUO
3423
-20°C
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
500 μg/mL
PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
P22304
Ids
A synthetic peptide corresponding to a sequence at the C-terminus of human Iduronate 2 sulfatase (430-448aa ELCREGKNLLKHFRFRDLE).
100 μg
Primary
Human
Antibody
IgG
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